Table 1.

Demographic and clinicopathologic characteristics in patients with excellent response (ER) vs. non-ER (including indeterminate, biochemical incomplete, and structural incomplete responses).

Characteristic	ER (n = 195)	Non-ER (n = 111)	P value
Age, years (mean ± SD)	42.3 ± 11.4	43.4 ± 10.5
>55 years	33 (16.9)	14 (12.6)	0.20
Male sex	41 (21.0)	36 (32.4)	0.03
LN dissection			0.23
Central	53 (27.2)	23 (20.7)
Central and lateral	28 (14.4)	23 (20.7)
Ultrasound features
Diameter >1 cm	90 (46.2)	48 (43.2)	0.13
Irregular margin	179 (87.4)	97 (91.8)	0.15
Microcalcification	116 (59.5)	60 (54.1)	0.21
Halo	191 (97.9)	106 (95.5)	0.19
Internal component			0.20
Solid	182 (93.3%)	107 (97.4%)
Solid-cystic	13 (6.7%)	4 (3.6%)
Echogenicity			0.40
Hyper	189 (96.9%)	109 (98.2%)
Hyper-iso	6 (3.1%)	2 (1.8%)
ATA risk stratification			0.33
High suspicion	183 (93.8%)	101 (91.0%)
Intermediate - very low suspicion	12 (6.2%)	10 (9.0%)
Vascularity			0.11
Type I	13 (6.7)	12 (10.8)
Type II	122 (62.6)	76 (68.5)
Type III	60 (30.8)	23 (20.7)
Elasticity score			0.54
0–2	24 (12.3)	14 (12.6)
3/4	171 (87.7)	97 (87.4)
CEUS features
Heterogeneous enhancement pattern	177 (90.8)	94 (84.7)	0.079
Enhancement grade			0.003
Blood-rich	60 (30.8)	54 (48.6)
Low	135 (69.2)	67 (51.4)
Relative arrival time of microbubble			0.15
Earlier or meantime	78 (40.0)	52 (46.8)
Later	117 (60.0)	59 (53.2)
Relative exit time of microbubble			0.22
Earlier or meantime	64 (32.8)	42 (37.8)
Later	131 (67.8)	69 (62.2)
Suspected LN on preoperative ultrasound	55 (28.2)	30 (27.0)	0.47
Pathological features
Capsule invasion	10 (5.2)	6 (5.5)	0.51
LN metastasis	82 (42.3)	48 (43.2)	0.53
Large-volume LN metastasis	30 (15.4)	18 (16.2)	0.48

Values are expressed as n (%) unless indicated. Number reported in bold are statistically significant.

SD, standard deviation; LN, lymph node; ATA, American Thyroid Association.