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. 2021 Jan 8;10:598238. doi: 10.3389/fonc.2020.598238

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Copyright © 2021 Zhang, Yu, Ni, Li, Bae, Choi, Yang, Kong and Zhu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interaction of DDX18 and Drosha. (A) DDX18 interacts with Drosha but not DGCR8. (B) The expression of microRNA-21 is correlated with that of DDX18. (C) MicroRNA expressions in the DDX18-KD cells. (D) DDX18 could affect the expression of microRNA-21. (E) MicroRNA-21 could bind to the 3′-untranslated region of PTEN and lead to degradation.