Table 1.

Association of DDX18 expression with clinicopathological characteristics in 585 patients with gastric cancer.

Clinicopathological characteristic	No. of cases	DDX18 expression				χ2	P-value
		Negative		Positive
		n = 205 (35.0%)		n = 380 (65.0%)
Gender
Male	400	139	34.8%	261	65.3%	0.048	0.827
Female	185	66	35.7%	119	64.3%
Age (years)
≤60	273	94	34.4%	179	65.6%	0.084	0.772
>60	312	111	35.6%	201	64.4%
Tumor location
Upper	76	22	28.9%	54	71.1%	967.9	<0.001***
Middle	115	36	31.3%	79	68.7%
Lower	309	116	37.5%	193	62.5%
Whole	80	29	36.3%	51	63.8%
Residual	5	2	40.0%	3	60.0%
Tumor size (cm)
<5	307	124	40.4%	183	59.6%	8.118	0.004**
≥5	278	81	29.1%	197	70.9%
Borrmann a
I	33	13	39.4%	20	60.6%	509.1	<0.001***
II	76	29	38.2%	47	61.8%
III	333	111	33.0%	223	67.0%
IV	66	18	27.3%	48	72.7%
Differentiation
High	15	8	53.3%	7	46.7%	248.5	<0.001***
Medium	146	63	43.2%	83	56.8%
Low	424	134	31.6%	290	68.4%
Vessel invasion
Negative	486	182	37.4%	304	62.6%	7.302	0.007**
Positive	99	23	23.2%	76	76.8%
Nerve invasion
Negative	504	188	37.3%	316	62.7%	8.159	0.004**
Positive	81	17	21.0%	64	79.0%
T stage
T1	76	34	44.7%	42	55.3%	586.7	<0.001***
T2	85	39	45.9%	46	54.1%
T3	151	52	34.4%	99	65.6%
T4	273	80	29.3%	193	70.7%
N stage
N0	228	106	46.5%	122	53.5%	596.6	<0.001***
N1	105	35	33.3%	70	66.7%
N2	113	25	22.1%	88	77.9%
N3	139	39	28.1%	100	71.9%
TNM stage
I	124	58	46.8%	66	53.2%	370.8	<0.001***
II	173	75	43.4%	98	56.6%
III	288	72	25.0%	216	75.0%

^aBorrmann for 509 cases of advanced gastric cancer. *P < 0.05, **P < 0.01, ***P < 0001.