Table 3.
Sensitivity, specificity, positive and negative predictive values of microscopy, Pf RDT and HSPf RDT compared to PCR as gold standard
| PCR Positive (n = 171) | PCR negative (n = 225) | Sensitivity % (CI95) | Specificity %(CI95) | PPV% (CI95) | NPV% (CI95) | |
|---|---|---|---|---|---|---|
| Microscopy | ||||||
| Positive (n = 87) | 70 | 17 | 40.0 (32.6–47.7) | 92.4 (88.0–95.5) | 80.5 (70.6–88.2) | 66.1 (60.6–71.4) |
| Negative (n = 310) | 105 | 205 | ||||
| Pf RDT | ||||||
| Positive (n = 110) | 99 | 11 | 56.5 (48.8–64.0) | 95.0 (91.3–97.5) |
90.0 (82.8–94.9) |
73.5 (68.0–78.5) |
| Negative (n = 287) | 76 | 211 | ||||
| HSPf RDT | ||||||
| Positive (n = 132) | 117 | 15 | 69.9 (59.3–73.8) | 93.2 (89.1–96.2) | 88.6 (82–93.5) | 78.1 (72.6–82.9) |
| Negative (n = 265) | 58 | 207 | ||||
PPV positive predictive value, NPV negative predictive value, CI95 95% confidence interval