Table 4.

Frequencies of IFNL3 and IFNL4 haplotypes concerning spontaneous HCV elimination (cases) and persistent HCV infection (controls)

SNPs	Haplotype	Haplotype Frequencies	Case, Control Frequencies	Chi Square	P Value	Pcorr Value†	OR (95%CI)‡, P Value	OR (95%CI)§, P Value
rs12980275_rs4803217_rs12979860_rs368234815_rs8099917	A_C_C_TT_T	0.562	0.667, 0.485	10.590	0.0011	0.0060	2.294 (1.412–3.727), 0.0007	Reference
	G_A_T_∆G_G	0.174	0.102, 0.227	8.543	0.0035	0.0190	0.380 (0.197–0.732), 0.0030	0.326 (0.167–0.638), 0.0008
	G_A_T_∆G_T	0.121	0.110, 0.130	0.289	0.5909	1.0000	0.819 (0.411–1.632), 0.5692	0.611 (0.301–1.241), 0.1706
	G_C_C_TT_T	0.043	0.037, 0.046	0.164	0.6855	1.0000	0.736 (0.241–2.253), 0.5901	0.543 (0.175–1.685), 0.2847
	A_A_T_∆G_T	0.020	0.008, 0.028	1.583	0.2083	0.7840	0.263 (0.030–2.280), 0.1934	0.196 (0.022–1.709), 0.1024
	G_A_T_TT_G	0.016	0.015, 0.016	0.013	0.9081	1.0000	0.894 (0.147–5.434), 0.9032	0.652 (0.106–3.997), 0.6415

^†P-value calculated using the permutation test and a total of 1000 permutations

^‡All other haplotypes pooled together were used as the reference

^§The most common haplotype was used as the reference