Table 1.
Differences of the baseline characteristics in AIS patients with and without HT
| Variables | Non‐HT (n = 256) | HT (n = 256) | p‐Value* |
|---|---|---|---|
| FAR, median (IQR) | 8.60 (7.25–10.8) | 10.29 (8.39–12.95) | <.001*** |
| Demographic parameters | |||
| Age (years), median (IQR) | 71.0 (60.5–77.0) | 71.0 (62.0–78.0) | .955 |
| Male, n (%), median (IQR) | 178 (69.5%) | 178 (69.5%) | 1 |
| BMI (kg/m2), median (IQR) | 23.4 (21.6–25.6) | 22.7 (20.8–24.5) | .017* |
| Marital status | |||
| Married, n (%) | 238 (93.0%) | 247 (96.5%) | .075 |
| Vascular risk factors | |||
| History of atrial fibrillation, n (%) | 26 (10.2%) | 97 (37.9%) | <.001*** |
| History of hypertension, n (%) | 178 (69.5%) | 163 (63.7%) | .160 |
| History of diabetes, n (%) | 75 (29.3%) | 64 (25.0%) | .274 |
| History of dyslipidemia, n (%) | 15 (5.9%) | 20 (7.8%) | .381 |
| Current smoking, n (%) | 78 (30.5%) | 81 (31.6%) | .774 |
| Current drinking, n (%) | 65 (25.4%) | 75 (29.3%) | .321 |
| Biochemistry and vital signs on admission | |||
| Large size of the infarction area, n (%) | 6 (2.3%) | 90 (35.2%) | <.001*** |
| Baseline SBP (mmHg), median (IQR) | 156.0 (144.0–170.0) | 148.5 (135.0–164.0) | <.001*** |
| Baseline DBP (mmHg), median (IQR) | 81.0 (73.0–91.5) | 82.0 (73.3–90.0) | .563 |
| Leukocyte counts (×109/L), median (IQR) | 6.57 (5.57–7.72) | 7.93 (6.35–9.90) | <.001*** |
| Platelets (×109/L), median (IQR) | 201.0 (173.0–236.5) | 183.0 (147.0–231.0) | .003** |
| Hemoglobin (g/L), median (IQR) | 136.0 (125.0–147.8) | 136.0 (126.0–146.0) | .659 |
| Glucose levels (mmol/L), median (IQR) | 5.1 (4.6–6.4) | 5.75 (4.80–7.08) | <.001*** |
| LDL‐C (mmol/L), median (IQR) | 2.65 (2.09–3.34) | 2.43 (1.72–3.06) | .001** |
| NIHSS on admission, median (IQR) | 3.0 (2.0–5.0) | 10.0 (6.0–13.0) | <.001*** |
| Stroke mechanisms | |||
| Atherosclerotic, n (%) | 233 (91.0%) | 172 (67.2%) | <.001*** |
| Cardioembolic, n (%) | 19 (7.4%) | 83 (32.4%) | |
| Lacunar, n (%) | 3 (1.2%) | 1 (0.4%) | |
| Other causes, n (%) | 1 (0.4%) | 0 (0%) | |
| Initial treatment before HT | |||
| Antiplatelets, n (%) | 231 (91.3%) | 137 (53.5%) | <.001 |
| Anticoagulants, n (%) | 24 (9.5%) | 80 (31.3%) | <.001 |
| Lipid‐lowering agents, n (%) | 241 (95.6%) | 219 (85.5%) | <.001 |
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; FAR, fibrinogen‐to‐albumin ratio; HT, hemorrhagic transformation; IQR, interquartile range; LDL‐C, low‐density lipoprotein‐cholesterol; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure.
*
p < .05;
**
p < .01;
***
p < .001