Table 2.
Baseline characteristics of patients with acute ischemic stroke in the high (≥9.51) and low (<9.51) FAR groups
| Variables | All patients | Low FAR (n = 261) | High FAR (n = 251) | p‐Value* |
|---|---|---|---|---|
| FAR, median (IQR) | 9.18 (7.61–11.3) | 7.71 (6.89–8.58) | 11.65 (10.65–13.59) | <.001*** |
| Demographic parameters | ||||
| Age (years), median (IQR) | 71.0 (61.0–77.0) | 69.0 (58.0–75.0) | 72.0 (63.0–80.0) | .001** |
| Male, n (%), median (IQR) | 356 (69.5%) | 186 (71.3%) | 170 (67.7%) | .385 |
| BMI (kg/m2), median (IQR) | 23.1 (21.0–25.2) | 23.5 (21.6–25.6) | 22.7 (20.8–24.5) | .006** |
| Marital status | ||||
| Married, n (%) | 485 (94.7%) | 246 (94.3%) | 239 (95.2%) | .625 |
| Vascular risk factors | ||||
| History of atrial fibrillation, n (%) | 123 (24.0%) | 54 (20.7%) | 69 (27.5%) | .072 |
| History of hypertension, n (%) | 341 (66.6%) | 164 (62.8%) | 177 (70.5%) | .065 |
| History of diabetes, n (%) | 139 (27.1%) | 66 (25.3%) | 73 (29.1%) | .334 |
| History of dyslipidemia, n (%) | 35 (6.8%) | 19 (7.3%) | 16 (6.4%) | .685 |
| Current smoking, n (%) | 159 (31.1%) | 75 (28.7%) | 84 (33.5%) | .248 |
| Current drinking, n (%) | 140 (27.3%) | 73 (28.0%) | 67 (26.7%) | .746 |
| Biochemistry and vital signs on admission | ||||
| Large size of the infarction area, n (%) | 96 (18.8%) | 31 (11.9%) | 65 (25.9%) | <.001*** |
| Baseline SBP (mmHg), median (IQR) | 154.0 (141.0–169.5) | 155.0 (141.0–169.8) | 150.0 (138.0–166.0) | .093 |
| Baseline DBP (mmHg), median (IQR) | 81.0 (73.0–90.0) | 82.5 (75.0–92.0) | 80.0 (72.0–89.0) | .099 |
| Leukocyte counts (×109/L), median (IQR) | 6.86 (5.62–8.25) | 6.77 (5.60–8.30) | 7.49 (6.27–9.36) | <.001*** |
| Platelets (×109/L), median (IQR) | 197.0 (168.0–235.5) | 192.0 (160.2–231.8) | 196.0 (162.0–291.0) | .704 |
| Hemoglobin (g/L), median (IQR) | 136.0 (125.0–147.0) | 140.0 (127.2–148.0) | 135.0 (123.3–155.0) | .003** |
| Glucose levels (mmol/L), median (IQR) | 5.20 (4.60–6.50) | 5.30 (4.60–6.58) | 5.45 (4.70–6.88) | .374 |
| LDL‐C (mmol/L), median (IQR) | 2.65 (2.00–3.32) | 2.50 (1.89–3.13) | 2.63 (1.88–3.35) | .498 |
| NIHSS on admission, median (IQR) | 4.0 (2.0–8.0) | 5.0 (2.0–9.0) | 6.0 (3.0–11.0) | .004** |
| Stroke mechanisms | ||||
| Atherosclerotic, n (%) | 405 (79.1%) | 217 (83.1%) | 188 (74.9%) | .056 |
| Cardioembolic, n (%) | 102 (19.9%) | 40 (15.3%) | 62 (24.7%) | |
| Lacunar, n (%) | 4 (0.8%) | 3 (1.1%) | 1 (0.4%) | |
| Other causes, n (%) | 1 (0.2%) | 1 (0.4%) | 0 (0%) | |
| Initial treatment before HT | ||||
| Antiplatelets, n (%) | 368 (72.3%) | 187 (72.2.%) | 181 (72.4%) | .960 |
| Anticoagulants, n (%) | 104 (20.4%) | 53 (20.5%) | 51 (20.4%) | .986 |
| Lipid‐lowering agents, n (%) | 460 (90.6%) | 235 (91.1%) | 225 (90.0%) | .676 |
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; FAR, fibrinogen‐to‐albumin ratio; HT, hemorrhagic transformation; IQR, interquartile range; LDL‐C, low‐density lipoprotein‐cholesterol; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure.
*
p < .05;
**
p < .01;
***
p < .001