TABLE 3.
Comparison of clinical variables according to the location of CMB
| Deep CMB | Strictly lobar CMB | |||||
|---|---|---|---|---|---|---|
|
CMB (−) N = 595 |
CMB (+) N = 259 |
p |
CMB (−) N = 684 |
CMB (+) N = 170 |
p | |
| Age, years, mean (SD) | 67.4 (12.7) | 70.2 (11.6) | .002 | 67.8 (12.6) | 70.1 (11.8) | .028 |
| Sex, female, n (%) | 276 (46.4) | 136 (52.5) | .100 | 328 (48.0) | 84 (49.4) | .733 |
| BMI, kg/m2, mean (SD) | 24.1 (3.2) | 24.7 (12.2) | .292 | 24.4 (7.9) | 24.0 (3.4) | .539 |
| Hypertension, n (%) | 355 (59.7) | 175 (67.6) | .029 | 419 (61.3) | 111 (65.3) | .332 |
| Diabetes mellitus, n (%) | 180 (30.3) | 78 (30.1) | .968 | 207 (30.3) | 51 (30.0) | .947 |
| Smoking, n (%) | 161 (27.1) | 52 (20.1) | .030 | 167 (24.4) | 46 (27.1) | .476 |
| Atrial fibrillation, n (%) | 107 (18.0) | 53 (20.5) | .393 | 126 (18.4) | 34 (20.0) | .637 |
| Previous stroke, n (%) | 96 (16.1) | 68 (26.3) | .001 | 127 (18.6) | 37 (21.8) | .344 |
| SBP, mm/Hg, mean (SD) | 148 (26) | 155 (31) | .001 | 150 (28) | 149 (27) | .819 |
| DBP, mm/Hg, mean (SD) | 85 (14) | 88 (16) | .008 | 86 (15) | 86 (16) | .886 |
| Hematocrit, %, mean (SD) | 40.6 (5.2) | 40.5 (6.8) | .747 | 40.7 (5.7) | 39.8 (5.7) | .060 |
| White blood cell, 109/L, mean (SD) | 8.1 (3.0) | 8.1(3.4) | .780 | 8.1 (3.2) | 8.1 (2.8) | .847 |
| Platelet, 109/L, mean (SD) | 233.7 (67.8) | 237.5 (84.6) | .478 | 235.1 (74.2) | 233.9 (69.8) | .849 |
| Fasting blood sugar, mmol/L, mean (SD) | 7.8 (3.2) | 7.7 (3.2) | .596 | 7.8 (3.3) | 7.7 (2.7) | .842 |
| LDL cholesterol, mmol/L, mean (SD) | 2.7 (0.8) | 2.7 (0.9) | .531 | 2.7 (0.8) | 2.7 (0.9) | .551 |
| Triacylglycerol, mmol/L, mean (SD) | 3.1 (2.1) | 3.0 (1.8) | .209 | 3.1 (2.0) | 3.2 (2.2) | .391 |
| hsCRP, mg/dl, mean (SD) | 5.6 (16.1) | 7.3 (25.4) | .236 | 6.2 (20.0) | 5.8 (16.5) | .820 |
| eGFR, ml/min/1.73 m2, mean (SD) | 83.7 (25.1) | 77.0 (27.6) | .001 | 81.2 (26.2) | 83.3 (25.5) | .339 |
| Mean baPWV, m/s, mean (SD) | 2.0 (0.5) | 2.2 (0.6) | <.001 | 2.0 (0.6) | 2.1 (0.5) | .168 |
Abbreviations: baPWV, brachial‐angle pulse wave velocity; BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; hsCRP, high‐sensitive C‐reactive protein; LDL, low‐density lipoprotein; SBP, systolic blood pressure; SD, standard deviation.