Table 2.
HR of incident PAD and CLI by magnesium quartile, Visit 2
| Outcome | Model | Serum magnesium |
|||
|---|---|---|---|---|---|
| Q1 (<1.5 mEq/L) | Q2 (1.5 mEq/L) | Q3 (1.6–1.7 mEq/L) | Q4 (>1.7 mEq/L) | ||
| N | 1587 | 2294 | 5805 | 2153 | |
| Events | 105 | 107 | 199 | 60 | |
| PAD | Model 1 | 2.57 (1.86–3.55) | 1.77 (1.29–2.44) | 1.26 (0.95–1.68) | Ref. |
| Model 2 | 1.64 (1.18–2.28) | 1.48 (1.07–2.04) | 1.23 (0.92–1.64) | Ref. | |
| Model 3 | 1.96 (1.40–2.74) | 1.67 (1.20–2.31) | 1.35 (1.01–1.80) | Ref. | |
| CLI | Model 1 | 2.50 (1.54–4.06) | 1.23 (0.73–2.06) | 0.89 (0.56–1.41) | Ref. |
| Model 2 | 1.25 (0.76–2.06) | 0.89 (0.53–1.50) | 0.82 (0.52–1.31) | Ref. | |
| Model 3 | 1.59 (0.95–2.66) | 1.04 (0.61–1.78) | 0.95 (0.58–1.53) | Ref. | |
Model 1: adjusted for sex, race and education. Model 2: further adjustment for smoking status, drinking status, hypertension, diabetes mellitus, prevalent coronary heart disease, prevalent stroke, total cholesterol, HDL cholesterol. Model 3: further adjustment for serum electrolytes (potassium, calcium and phosphate), eGFR, iPTH and FGF-23. Q, quartile.