Table 3.

HR of incident PAD by eGFR, Visit 2

	eGFR ≥60		eGFR <60		P-for-interaction
N	11 606		233
Events	436		35
Variable	HR (95% CI)	P-value	HR (95% CI)	P-value
Higher calciuma	1.06 (0.86–1.29)	0.60	0.68 (0.31–1.48)	0.33	0.17
Higher phosphorusa	1.01 (0.83–1.24)	0.90	1.22 (0.53–2.78)	0.64	0.95
Higher iPTHa	1.07 (0.88–1.30)	0.52	0.51 (0.22–1.22)	0.13	0.93
Higher FGF-23a	1.09 (0.90–1.32)	0.39	1.40 (0.42–4.73)	0.58	0.84
Higher calciumb	0.59 (0.33–1.07)	0.08	2.10 (0.44–9.97)	0.35	0.43
Higher phosphorusb	2.01 (1.36–2.95)	<0.001	1.87 (0.64–5.49)	0.25	0.82
Higher iPTHb	1.09 (0.76–1.55)	0.64	2.24 (0.94–5.36)	0.07	0.01
Higher FGF-23b	1.43 (1.10–1.86)	0.01	0.94 (0.37–2.39)	0.90	0.60

Adjusted for age, sex, race, education, smoking status, drinking status, hypertension, diabetes mellitus, prevalent coronary heart disease, total cholesterol and HDL cholesterol.

^aCalcium, phosphorus, iPTH and FGF-23 above versus below their median values.

^bCalcium, phosphorus, iPTH and FGF-23, above versus below clinical cut-points.