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. 2021 Jan 8;10:526866. doi: 10.3389/fonc.2020.526866

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Copyright © 2021 Mu, Zhao, Chen, Zhao, Yan, Peng, Zhu, Yang, Lan, Gu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially methylated RNAs are involved in Wnt biological pathway of IL-37 treated A549 cells. (A) Wnt-5a, within which m6A was hypermethylated (IL-37 treated A549 cells vs untreated control) near the start codon; (B) Wnt-5b, within which m6A was hypomethylated upstream of the 5′ UTR; (C) Expression of Wnt5a/5b in IL-37 treated A549 cells. Data are mean ± SEM. *P < 0.05.