TABLE 2:
RPA Interacting Proteins
| RPA Interacting Protein | Region of interaction on RPA | Species | Reference |
|---|---|---|---|
| Activation induced Cytidine Deaminase (AID) | RPA32 | h | (101) |
| ATRIP | RPA70(DBD F) | h | (102–104) |
| Bloom Syndrome Helicase (BLM) | RPA70(168–308) | h | (105) |
| BRCA2 | ? | h | (106) |
| DDX11 | ? | h | (107) |
| DNA2 | RPA70(DBD F and C-term) | sc | (108,109) |
| EXO5 | RPA70(DBD-F) | h | (110) |
| FACT | RPA70(DBD F), RPA32 | sc | (111,112) |
| FancJ | ? | h | (113–116) |
| FBH1, F Box Helicase 1 | ? | h | (117) |
| H3-H3 | RPA70(DBD-F) | sc | (112) |
| Heat Shock Factor 1 | RPA70 | h | (118) |
| HELB | RPA70(DBD F) | h | (119,120) |
| HERC2 | RPA70 | h | (121) |
| HIRA | RPA70(DBD-C) | h | (22) |
| HLTF, Helicase Like Transcription Factor | RPA70? | h | (121,122) |
| Mre11-Rad50-Nbs1 | RPA70(DBD F) | h | (123–126) |
| Nucleolin | RPA14 | h | (127,128) |
| p53 | RPA70(1–120) | h | (129–132) |
| Papilomavirus E1 | RPA70(181–291) | h | (133,134) |
| Parvovirus NS1 | RPA70, RPA32 | h | (135) |
| PCNA | RPA70 | bo, h | (136,137) |
| Pol-prim | RPA70(1–327), RPA32 | bo,h | (5,138,139) |
| Polymerase delta | RPA70 | h | (140) |
| PP2A | ? | h | (141) |
| PRP19/BCAS2 | RPA70(DBD-F, DBD-C) | h | (121,142,143) |
| Rad17 | RPA70(DBD F) | h, sc | (144–146) |
| Rad18 | RPA70(167–452), RPA32 | sc | (147) |
| RAD51, Rad51 | RPA70(181–291) | h, sc | (148,149) |
| RAD52, Rad52 | RPA70(169–326), RPA32(224–271) | h, sc | (150–154) (155) |
| RAD9 | RPA70, RPA32 | h | (156) |
| RECQL1 | RPA70 | h | (113,157,158) |
| RECQL5B | ? | h | (159,160) |
| RFC | RPA70 | h, sc | (140,161) |
| RFWD3 | RPA70, RPA32 WH | h | (121,162,163) |
| RNF4 | ? | h | (164) |
| scPfh1 | RPA70, RPA32, RPA14 | sc | (165,166) |
| scPif1 | ? | sc | (167) |
| SMARCAL1 | WH | h | (168–170) |
| SV40 T antigen | RPA70(181–327), WH | h, sc | (133,134,171–173) |
| Tipin | WH | h | (174) |
| Uracil-DNA glycosylase (UDG) | RPA32(163–217) | h | (152,175,176) |
| Werner Syndrome Helicase (WRN) | RPA70(168–308) | h | (105,177) |
| XPA | RPA70(183–296), WH | h | (152,175,178–181) |
| XPF-ERCC1 | ? | h | (83,182,183) |
| XPG | ? | h | (83,183,184) |
A list of proteins that interact with RPA complied from a variety of reviews and sources (100,185,186). The site on RPA that the interaction occurs at, if it has been identified, is listed. The species in which the interaction was identified is noted (h:human, sc: saccharomyces cerevisiae, bo:bovine.