Table 1.
Model scenario settings.
| Scenario | Achievable Cell Concentration (Cells/Ml) | FGF-2 1 Conc. (G/L) | FGF-2 Cost (USD/G) | Glucose Conc. in Basal Media (Mol/L) | Glucose Consumption Rate Per Cell (Mol/H Cell) | Hours Per Doubling (H) | Maturation Time (H) |
|---|---|---|---|---|---|---|---|
| 1 | 1.00 × 107 | 1.00 × 10−4 | 2.05 × 106 | 1.78 × 10−2 | 4.13 × 10−13 | 24.0 | 240 |
| 2 | 9.5 × 107 | 5.00 × 10−5 | 1.00 × 106 | 2.67 × 10−2 | 2.07 × 10−13 | 16 | 156 |
| 3 | 9.5 × 107 | 5.00 × 10−5 | 0 | 2.67 × 10−2 | 2.07 × 10−13 | 16 | 156 |
| 4 | 2.00 × 108 | 0 | 0 | 3.56 × 10−2 | 4.13 × 10−14 | 8 | 24 |
1 Fibroblast growth factor 2 (FBF-2).