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. 2020 Dec 22;13(1):6. doi: 10.3390/pharmaceutics13010006

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — Reagents and conditions: (a) 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), 1-hydroxybenzotriazole (HOBt), N-methylmorpholine (NMM), N,N-dimethylformamide (DMF), rt, 15 h.