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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Cancer Lett. 2020 Dec 21;500:220–227. doi: 10.1016/j.canlet.2020.12.023

Fig. 2.

Fig. 2.

RAD51 foci formation is inhibited by YTR107. (A) A549 cells were exposed to 25 μM YTR107 for 30 min prior to, during and for 4 h after 0 or 10 Gy. Cells were immunostained for RAD51 and DAPI counterstained. (B) Quantification of individual foci per nuclei is expressed as box and whisker plots, max to min, and represents the average of four independent experiments. N = 132 for 0 Gy DMSO; N = 109 for 0 Gy YTR107; N = 365 for 10 Gy (DMSO); N = 208 for 10 Gy YTR107. (C) Cells were immunostained for RAD 51 and Geminin, a S/G2 phase marker. (D) Quantification of individual RAD51 foci per nuclei in Geminin expressing cells. white line = 10 μm.