TABLE 1.
Prevalence (% positive), 95% confidence intervals, and mean fluorescence intensity of IgG responses to rPvMSP8, rPvMSP1-19, and rPvMSP8+1 in P. vivax-infected patient and uninfected healthy individual serum samples
| Protein | No. of P. vivax infected patient samples |
95% CIb (%) | MFI | No. of uninfected healthy samples |
95% CI (%) | MFI | P value | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Positivea | Negative | Total no. (%) | Positive | Negativec | Total no. (%) | ||||||
| rPvMSP8 | 82 | 30 | 112 (73.2) | 64.3–80.6 | 17,867 | 3 | 77 | 80 (96.3) | 89.6–98.7 | 1,363 | <0.0001 |
| rPvMSP1-19 | 90 | 22 | 112 (80.4) | 73.1–87.7 | 15,572 | 5 | 75 | 80 (93.8) | 88.4–99.0 | 3,346 | <0.0001 |
| rPvMSP8+1 | 79 | 33 | 112 (70.5) | 62.0–78.9 | 17,611 | 4 | 76 | 80 (95.0) | 92.6–97.4 | 6,427 | <0.0001 |
a
Sensitivity is the % positive in P. vivax-infected patient samples.
b
CI, confidence interval.
c
Specificity is the % negative in uninfected healthy samples.