Figure 1.

Schematic representation of neural tube development, neural crest cells (NCCs) migration, and some associations of NCCs with phenotypic traits of the domestication syndrome in mammals. The upper part of the schematics is made according to Marieb and Hoehn (2018) [27] and Kaltschmidt et al. (2018) [28]. The Waddington’s epigenetic landscape (“canalization”) on the right side illustrates contribution of epigenetic changes on NCCs migration, differentiation, and proliferation, and is made according to Strobl-Mazzulla and Bronner (2014) [29]. For the purpose of this schematic representation, no distinction is made between anterior (cephalic) and posterior somatic NCCs.