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. 2021 Jan 18;14:179–185. doi: 10.2147/IJGM.S288360

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© 2021 Gong et al.

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CircRNA_104565 acts as a ceRNA for miR-134 to promote cell proliferation in PTC. (A) The potential binding sites of circRNA_104565 and miR-134 were predicted by miRDB and starbase tool. (B) Luciferase reporter assay had confirmed complementary combinations between circRNA_104565 and miR-134. (C) MiR-134 expressions were detected by qRT-PCR. (D) MiR-134 expression was significantly decreased in PTC tissues compared to normal tissues. (E) Pearson correlation analysis revealed circRNA_104565 expression was inversely correlated with miR-134 in PTC tissue. (F) Cell proliferations were detected by CCK8 assay. *P < 0.05.