Table 1.
Correlations of LARGE1 Expression with Clinicopathological Features in Stage I–III NSCLC Patients
| Clinical Features | Low LARGE1 | High LARGE1 | P-value |
|---|---|---|---|
| N | 489 | 492 | |
| Age (years) | 0.002 | ||
| <65 | 208 (43.882%) | 164 (34.238%) | |
| ≥65 | 266 (56.118%) | 315 (65.762%) | |
| Gender | 0.937 | ||
| Female | 197 (40.286%) | 197 (40.041%) | |
| Male | 292 (59.714%) | 295 (59.959%) | |
| Smoking history | 0.065 | ||
| Lifelong non-smoker | 43 (8.996%) | 43 (8.977%) | |
| Current smoker | 123 (25.732%) | 121 (25.261%) | |
| Current reformed smoker for < or = 15 years | 217 (45.397%) | 188 (39.248%) | |
| Current reformed smoker for > 15 years | 89 (18.619%) | 124 (25.887%) | |
| Current reformed smoker, duration not specified | 6 (1.255%) | 3 (0.626%) | |
| Histology | 0.038 | ||
| Lung adenocarcinoma | 259 (52.965%) | 228 (46.341%) | |
| Lung squamous cell carcinoma | 230 (47.035%) | 264 (53.659%) | |
| Pathological TNM stages | <0.001 | ||
| I | 230 (47.035%) | 293 (59.553%) | |
| II | 155 (31.697%) | 134 (27.236%) | |
| III | 104 (21.268%) | 65 (13.211%) | |
| Pathological T stages | <0.001 | ||
| T1 | 112 (22.904%) | 167 (33.943%) | |
| T2 | 295 (60.327%) | 256 (52.033%) | |
| T3–4 | 82 (16.769%) | 69 (14.024%) | |
| Pathological N stages | <0.001 | ||
| N0 | 288 (59.627%) | 347 (71.399%) | |
| N1 | 118 (24.431%) | 100 (20.576%) | |
| N2 | 77 (15.942%) | 39 (8.025%) |