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. 2021 Jan 22;16(1):e0245443. doi: 10.1371/journal.pone.0245443

Table 4. Self-reported symptoms that were aggravated by regular cigarette smoking and self-reported symptoms that had improved after the participants had started EC use (n = 400).

Symptoms that the participants suffered from when they smoked regular cigarettes N (%) Dual cigarette users
N (%)
E-cigarette only users
N (%)
P-value
Chest wheezing 155 (38.8) 101 (44.5) 54 (31.2) 0.007
Shortness of breath 211 (52.8) 130 (57.3) 81 (46.8) 0.043
Sputum production 268 (67.0) 176 (77.5) 92 (53.3) <0.001
Cough 218 (54.5) 138 (60.8) 80 (46.2) 0.005
Nothing 48 (12.0) 26 (11.5) 22 (12.7) 0.757
Other symptoms (i.e., chest discomfort, headaches, blurred vision, and stomach upset) 8 (2.0) 4 (1.8) 4 (2.3) 0.731
Symptoms that had improved after the participants had started EC use N (%)
Cough 192 (48.0) 112 (49.3) 80 (46.2) 0.546
General well-being 210 (52.5) 118 (52.0) 92 (53.2) 0.840
Breathing 224 (56.0) 134 (59.0) 90 (52.0) 0.186
Sputum production 228 (57.0) 138 (60.8) 90 (52.0) 0.046
Other symptoms (i.e., increased appetite was reported) 1 (0.3) 1 (0.4) 0 (0.0) 1.000

* Pearson’s Chi-squared test and Fisher’s exact test were used.