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(A) Quantification of extracellular IL-6 accumulation post ORN06 treatment at 0–1 μg/mL and 10 ng/ml M-CSF. (B) Quantification of extracellular IL-6 levels for control, ORN06 and then buffer, and ORN06 and then SAP-treated human PBMC cultured in presence of 10 ng/ml M-CSF. Values are mean ± SEM, n = 6 (human PBMC from 3 males and 3 females). * p < 0.05 (1-way ANOVA, Bonferroni’s test).
