Table 2.
Summary of clinical applications of umbilical cord mesenchymal stromal cells.
| Disorders | Disease Treated | Reference |
|---|---|---|
| Neurologic | Spinal cord injury | [149] |
| Multiple Sclerosis | [150] | |
| Stroke | [151,152] | |
| Traumatic brain injury | [153] | |
| Amyotrophic lateral sclerosis | [154] | |
| Autism | [155] | |
| Cerebral palsy | [156] | |
| Hypoxic ischemic encephalopathy | [157] | |
| Vascular dementia | [158] | |
| Cardiovascular | Acute myocardial infarction | [159] |
| Systolic heart failure | [160] | |
| Hepatic | Liver failure | [161,162] |
| Transplant rejection | [163] | |
| Hematologic | Graft versus host disease (acute, chronic) | [164,165] |
| Leukemia | [166] | |
| Aplastic anemia | [167] | |
| Thrombocytopenia | [168] | |
| Immunologic | Rheumatoid arthritis | [169] |
| Ulcerative colitis | [170] | |
| Systemic lupus erythematosus | [171] | |
| HIV infection | [172] | |
| Pulmonary | Severe idiopathic pulmonary fibrosis | [173] |
| Bronchopulmonary dysplasia | [174] | |
| Endocrine | Diabetes (Type I, Type II) | [175] |
| Diabetic foot ulcer | [176] | |
| Ophthalmologic | Retinitis pigmentosa | [177] |
| Musculoskeletal disorders | Becker muscular dystrophy | [178] |
| Bone nonunion (fractured, infected) | [179,180] | |
| Duchenne muscular dystrophy | [181] | |
| Osteonecrosis of femoral head | [182] | |
| Cartilage regeneration | [183] | |
| Dermatologic | Psoriasis vulgaris | [184] |
| Cesarean scar defect | [185] |