Table 3. Haematological management by country.
| Blood products | UK n = 162 | Australia n = 61 | Italy n = 99 | the Netherlands n = 179 | France n = 126 | Denmark n = 288 | P-value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of RBC units | Median (IQR) | 10 | (8–14) | 11 | (9–14) | 9 | (8–11) | 11 | (9–15) | 10 | (9–12) | 11 | (8–15) | <0·001 |
| Received Fresh frozen plasma | n (%) | 162 | (100) | 59 | (96·7) | 84 | (84·8) | 179 | (100) | 126 | (100) | 247 | (85·8) | <0·001 |
| Fresh frozen plasma | Median (IQR) | 6 | (4–8) | 6 | (4–8) | 4 | (2–8) | 6 | (4–8) | 7 | (5–9) | 6 | (4–8) | <0·001 |
| Received Platelets | n (%) | 126 | (77·8) | 51 | (83·6) | 40 | (40·4) | 179 | (100) | 126 | (100) | 205 | (71·2) | <0·001 |
| Platelets | Median (IQR) | 1 | (1–2) | 1 | (1–2) | 0 | (0–2) | 2 | (1–3) | 1 | (1–3) | 2 | (0–3) | <0·001 |
| Source of concentrated fibrinogen administered | No | 58 | (35·8) | 8 | (13·6) | 62 | (62·6) | 116 | (64·8) | 27 | (22·3) | - | - | <0·001 |
| Yes | 104 | (64·2) | 51 | (86·4) | 37 | (37·4) | 63 | (35·2) | 94 | (77·7) | - | - | ||
| Missing | 0 | 2 | 0 | 0 | 5 | - | - | |||||||
| Fibrinogen concentrate used | No | 152 | (93·8) | 54 | (100) | 62 | (62·6) | 116 | (64·8) | 27 | (22·3) | - | - | <0·001 |
| Yes | 10 | (6·2) | 0 | (0) | 37 | (37·4) | 63 | (35·2) | 94 | (77·7) | - | - | ||
| Missing | 0 | 7 | 0 | 0 | 5 | - | - | |||||||
| Cryoprecipitate used | No | 55 | (35·5) | 8 | (13·6) | - | - | - | - | - | - | - | - | 0·002 |
| Yes | 100 | (64·5) | 51 | (86·4) | - | - | - | - | - | - | - | - | ||
| Missing | 7 | 2 | - | - | - | - | - | - | - | - | ||||
| Number of units of cryoprecipitate | Median (IQR) | 2 | (0–2) | 1 | (1–2) | - | - | - | - | - | - | - | - | 0.07 |
| Use of cell salvage | No | 115 | (74·2) | 46 | (85·2) | - | - | - | - | - | - | - | - | 0·098 |
| Yes | 40 | (25·8) | 8 | (14·8) | - | - | - | - | - | - | - | - | ||
| Missing | 7 | 7 | - | - | - | - | - | - | - | - | ||||
| If Yes, amount transfused (ml) | Median (IQR) | 1150 | (500–1900) | 884 | (565–1377) | - | - | - | - | - | - | - | - | 0.95 |
| Recombinant Factor VIIa | No | 149 | (92) | 48 | (90·6) | 86 | (86·9) | 151 | (84·4) | 103 | (85·1) | - | - | 0·224 |
| Yes | 13 | (8) | 5 | (9·4) | 13 | (13·1) | 28 | (15·6) | 18 | (14·9) | - | - | ||
| Missing | 0 | 8 | 0 | 0 | 5 | - | - | |||||||
| Tranexamic acid | No | 87 | (53·7) | 41 | (74·5) | 57 | (57·6) | 45 | (25·1) | 47 | (39·2) | - | - | <0·001 |
| Yes | 75 | (46·3) | 14 | (25·5) | 42 | (42·4) | 134 | (74·9) | 73 | (60·8) | - | - | ||
| Missing | 0 | 6 | 0 | 0 | 6 | - | - | |||||||
| Any fluid used during resuscitation** | No | 4 | (2·5) | 42 | (77·8) | 0 | (0) | 0 | (0) | 0 | (0) | - | - | <0·001* |
| Yes | 157 | (97·5) | 12 | (22·2) | 55 | (100) | 167 | (100) | 108 | (100) | - | - | ||
| Missing | 1 | 7 | 44 | 12 | 18 | - | - | |||||||
| Total amount (ml) | 4000 | (3000–6000) | 3500 | (3000–5000) | 4500 | (3000–6000) | 0·205 | |||||||
| Colloid | Yes | 139 | (88·5) | - | - | 49 | (98) | 160 | (96·4) | 87 | (82·9) | - | - | <0·001* |
| Missing | 5 | - | - | 49 | 13 | 21 | - | - | ||||||
| If Yes, amount transfused (ml) | Median (IQR) | 1000 | (650–2000) | - | - | 1000 | (500–1500) | 1500 | (1000–2000) | - | - | - | - | <0·001 |
| Crystalloid | Yes | 152 | (95) | - | - | 49 | (100) | 137 | (100) | 103 | (95·4) | - | - | 0·013* |
| Missing | 2 | - | - | 50 | 42 | 18 | - | - | ||||||
| If Yes, amount transfused (ml) | Median (IQR) | 3000 | (1500–4000) | - | - | 2500 | (1700–3500) | 2500 | (1600–4300) | - | - | - | - | 0·442 |
*Used Fisher’s exact test.
**Australia only recorded use of 5 and 25% albumin administration.
Missing data were not included in the percentage. A dash indicated that the country did not collect data on that specific variable.