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. 2021 Jan 22;16(1):e0245373. doi: 10.1371/journal.pone.0245373

Table 1. Summary of first-line therapy for exacerbations in the outpatient setting and immediately post exacerbation.

Initial prescription (outpatient), %a Following an acute exacerbation, %a
Inhaled therapies
SABA 91.7 85.7
SAMA 57.7 46.7
LABA 57.7 65.3
LAMA 59.2 42.4
ICS/LABA 38.2 51.9
LABA/LAMA 58.2 79.8
Nebulization
SABA 90.9 64.0
SAMA 84.4 61.9
Corticosteroids 37.0 18.3
Systemic corticotherapy 68.5 21.7
Antibiotic therapy 87.9 40.5
Diuretics 14.5 5.9
Bronchial drainage physiotherapy 86.5 85.6
Prevention LMWH 5.8 9.3
Mucomodulators 19.8 11.4

aPercentage of respondents replying ‘yes’ to whether they prescribe a particular therapy in a particular setting (from a yes/no option).

ICS, inhaled corticosteroid; LABA, long-acting β2 agonists; LAMA, long-acting muscarinic antagonists; LMWH, low-molecular-weight heparin; SABA, short-acting β2 agonists; SAMA, short-acting muscarinic antagonists.