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. 2021 Jan 22;16(1):e0245864. doi: 10.1371/journal.pone.0245864

Table 1. Demographic characteristics of responders.

No. (%)
Characteristics Total PD Control P-value
Overall 71 (100) 39 (54.9) 32 (45.0)
Sex
Male 30 (42.2) 25 (64.1) 5 (15.6) < 0.001
Female 41 (57.7) 14 (35.8) 27 (84.3)
Age, y
<70 25 (35.2) 11 (15.4) 14 (19.7) 0.078
70–79 33 (46.4) 18 (46.1) 15 (46.8)
>80 13 (18.3) 10 (25.6) 3 (9.3)
Living alone 3 (4.2) 3 (7.6) - 0.109
Disease duration, years
< 5 22 (56.4) - -
≥ 5 17 (43.5) - -
HY stage
stage 0–2 12 (30.7) - -
stage 3, 4 27 (69.2) - -
Non-motor symptoms
Cognitive impairment 6 (15.3) - -
Hallucinations 4 (10.2) - -
RBD 6 (15.3) - -
L-DOPA, mg
< 600 30 (76.9) - -
≥ 600 9 (23.0) - -
Other medications
Dopamine agonist 15 (38.4) - -
Psychiatric medicines 8 (20.5) - -
Sleeping medicines 13 (33.3) - -
MDS-UPDRS part 2, 17 (10–20.5) - -
median (IQR), n = 36*

Abbreviations: HY, Hoehn & Yahr; RBD, REM sleep behavior disorder; MDS-UPDRS, Movement Disorder Society Unified Parkinson's Disease Rating Scale; IQR, interquartile range.

*Of the 39 participants, 36 responded to the question about MDS-UPDRS part 2.