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. 2020 Jun 9;103(4):892–906. doi: 10.1093/biolre/ioaa101

Figure 1.

Figure 1

Effects of soy-based diets on testicular androgen secretion. Male rats at 21 (n=45), 35 (n=36) and 75 days of age (n=18) were maintained on a control diet (Con), whole soybean diet (SBM) or control diet supplemented with genistein and daidzein (G+D) for 14 days. After sacrifice, serum were separated from blood to measure testosterone (T) concentration (A, B, C). Testicular explants were obtained and incubated in DMEM/Ham’s F-12 culture medium for 3 h without (D, E, F) or containing 100 ηg/ml ovine LH (NIDDK, NIH) (G, H, I). Aliquots of spent media were analyzed to measure T concentrations. Hormone concentrations were determined by RIA (*P < 0.05, **P < 0.001).