Examples of outlier cases. Transversal (left) and sagittal (right) images with CTV contours by RTTs (blue) for the seven fractions that were judged to need larger, potentially clinically relevant, adaptations, as judged by Observer 3, next to the adapted contours by Observer 1 (yellow) and/or Observer 2 (red). For Patient 19, fraction 3 and 5 are not displayed separately, since all contours were almost identical (shown here: fraction 3). For Patient 2, for fraction 2, 4, and 5 the CTV contour by the RTTs included the neurovascular bundle at the apex. For Patient 4, fraction 4, the seminal vesicles were missed in the CTV contour by the RTTs and the CTV contour was too wide towards the base and ventrally at the mid-prostate. For Patient 5 and 19, a larger part of the base of the prostate was left out. RTTs = Radiation therapists.