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. 2021 Jan 22;11:2089. doi: 10.1038/s41598-020-80708-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Concentration of ROS produced in BHK-21 cells after (a) 24 h, (b) 48 h, (c) 96 h and (d) 120 h of incubation with PVC (■) and PMMA ( ) NPs at different concentrations. The data for 72 h incubation were given in the supporting information, Figure S9. The results are given as % of the ROS production with respect to the control (untreated cells) and are the mean ± SEM of three experiments. Statistical analysis was done by one-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001) compared to control cells with no particles added.

Inline graphic — Concentration of ROS produced in BHK-21 cells after (a) 24 h, (b) 48 h, (c) 96 h and (d) 120 h of incubation with PVC (■) and PMMA ( ) NPs at different concentrations. The data for 72 h incubation were given in the supporting information, Figure S9. The results are given as % of the ROS production with respect to the control (untreated cells) and are the mean ± SEM of three experiments. Statistical analysis was done by one-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001) compared to control cells with no particles added.