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. 2021 Jan 22;7:2. doi: 10.1038/s41537-020-00131-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — y-axis shows target trait variance explained, upwards for positive and downwards for negative associations; with P-values of association shown on bars. The green bars show the best-fit schizophrenia PRS and the corresponding target traits (x-axis), and the red bars show the association results when using the genome-wide significant (GW-significant) schizophrenia PRS instead (based on the 108 sentinel schizophrenia SNPs). See Supplementary Table 2 for details and to inspect the selection of these 20 results among the top results.