Fig. 4. Identification of a discriminatory IgG-reactive wheat epitope.
a Multiple sequence alignment of three alpha purothionin peptides, which are b preferentially IgG reactive in the wheat non-allergic and sensitized populations, versus wheat allergic individuals. c IgE reactivities to the alpha purothionin epitope among the same three patient populations. d Comparison of the IgE versus the IgG reactivities to the alpha purothionin epitope. For b–d—wheat allergic (n = 32), wheat non-allergic (n = 27), and wheat sensitized (n = 27). Source data are provided as a Source Data file.