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. 2021 Jan 22;12:547. doi: 10.1038/s41467-020-20750-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A Boxplots of qPCR expression for Lss, Dhcr7, Idi1, and Hmgcr measured from liver samples of B6 mice fed either chow (control) diet or drug (BIBB515, Lss inhibitor) diet. B Boxplots of fasted glucose measured from blood at the end of 10 days of diet. C Boxplots of two key gluconeogenesis genes, PEP Carboxykinase (Pck1), and Glucose-6-Phosphatase (G6Pase), measured from qPCR of liver samples. n = 11 animals with control diet and 11 animals with drug diet. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5x interquartile range; points, all individual data points.