Fig. 7. Silencing ESRP1 reversed circ-NOLC1’s function as an oncogene.
Silencing ESRP1 inhibited cell viability A and clonal formation B, induced apoptosis C, and reduced cell migration D and invasion E in circ-NOLC1-overexpressing CAOV3 cells, and inhibited RhoA and CDK1 protein expression (F). Results are representative of three separate experiments; data are expressed as the mean ± SD. Comparisons between two groups were analyzed using a two-sided Student’s t test. *p < 0.05.