Table 1.
Patient characteristics in the three study groups/subgroups
| No DHEAS Supplementation A1 (n = 128) | DHEAS supplementation A2 (n = 137) | Normal control B (n = 145) | No metformin treatment C1 (n = 137) | Metformin treatment C2 (n = 134) | |
|---|---|---|---|---|---|
| Female age (years) | 35.31 ± 3.7 | 34.47 ± 3.7# | 32.12 ± 2.5 | 33.45 ± 2.1 | 32.28 ± 2.3* |
| Infertility duration (years) | 5.2 ± 1.3 | 5.5 ± 2# | 4.8 ± 1.5 | 5.1 ± 1.8 | 6 ± 2.5* |
| BMI (kg/m2) | 24.3 ± 2.5 | 23.08 ± 4.0# | 24.69 ± 3.3 | 25.5 ± 2.7 | 25.4 ± 3.1* |
| AMH (ng/ml) | 1.03 ± 0.08 | 1.2 ± 0.06# | 2.8 ± 0.9 | 6.8 ± 1.1 | 7.1 ± 1.0* |
| AFC | 5.1 ± 0.7 | 5.8 ± 1.0# | 12.2 ± 2.5 | 20.45 ± 1.9 | 21.21 ± 2.3* |
| Baseline D3 DHEAS (μg/dl) | 60 ± 18 | 69 ± 16# | 145 ± 28 | 332 ± 46 | 348 ± 42* |
| Indications for IVF | |||||
| Previous 2–3 failed IVF cycles of no/poor fertilisation | 83 | 80# | 00 | 94 | 98* |
| Fresh IVF with previous 3–4 failed IUI due to unexplained infertility | 45 | 57# | 36 | 43 | 36* |
| Fresh IVF cycles with bilateral tubal block/hydrosalpinx | 00 | 00 | 109 | 00 | 00 |
Values are mean ± SD
#A2 vs. A1, *C2 vs. C1 = p > 0.05 = non-significant