Table 2.
Parameters | 2a | 2b | ||
---|---|---|---|---|
Oral DHEAS supplementation subgroup A2 (n = 137) | No DHEAS supplementation lower control subgroup A1 (n = 128) | Metformin treatment subgroup C2 (n = 137) | No metformin treatment higher control subgroup C1 (n = 134) | |
Mean eggs retrieved | 7.76 ± 3.0 | 4.83 ± 2.0a | 22.62 ± 5.4 | 20.59 ± 5.6d |
Fertilisation, % | 79.83 ± 3.3 | 55.68 ± 3.14a | 79.04 ± 2.9 | 53.04 ± 2.9a |
Cleavage, % | 78.5 ± 2.86 | 53.39 ± 3.16a | 76.24 ± 4.01 | 52.09 ± 4.9a |
Blastocyst formation, % | 42.61 ± 5.14 | 22.26 ± 3.09a | 40.58 ± 4.3 | 20.17 ± 3.04a |
Live birth (n), % | (51) 37.23 ± 4.8 | (21) 16.41 ± 3.7b | (48) 35.04 ± 4.9 | (20) 14.93 ± 3.5b |
Early miscarriage, % | 3.65 ± 0.19 | 10.16 ± 0.3c | 3.65 ± 0.19 | 9.7 ± 0.3e |
Values are mean ± SD (standard deviation) p < 0.05 = significant
ap < 0.0001; bp = 0.0002; cp = 0.035; dp = 0.0025; ep = 0.04