Table 1.
Patient demographics
| Protocol | ||||
|---|---|---|---|---|
| Overall | LH/HCG+6 | hCG+7 | ASD* | |
| n (%) | 347 (100%) | 177 (51%) | 170 (49%) | |
| Age at first transfera | 36.5 (3.8) | 36.1 (3.8) | 36.9 (3.8) | 0.187 |
| Age at retrieval | 35.9 (3.8) | 35.5 (3.7) | 36.2 (3.9) | 0.187 |
| Number of transfers | 1.3 (0.6) | 1.3 (0.7) | 1.30 (0.6) | 0.109 |
| Nulliparous, n (%) | 227 (65.4) | 131 (74.0) | 96 (56.5) | 0.375 |
| BMI | 25.1 (5.2) | 25.2 (5.4 | 25.0 (5.1) | 0.040 |
| Non-smoker, n (%) | 329 (94.8) | 167 (94.4) | 162 (95.3) | 0.043 |
| Race, n (%) | 0.551 | |||
| South Asian | 88 (25.4) | 55 (31.1) | 33 (19.4) | |
| East Asian | 97 (28.0) | 59 (33.3) | 38 (22.4) | |
| White | 140 (40.3) | 49 (27.7) | 91 (53.5) | |
| Black or African American | 4 (1.2) | 3 (1.7) | 1 (0.6) | |
| Other | 16 (4.6) | 10 (5.6) | 6 (3.5) | |
| Unknown | 2 (0.6) | 1 (0.6) | 1 (0.6) | |
| Infertility diagnosis, n (%) | ||||
| Diminished ovarian reserve | 79 (22.8) | 33 (18.6) | 46 (27.1) | 0.201 |
| Ovulatory dysfunction | 14 (4.0) | 9 (5.1) | 5 (2.9) | 0.109 |
| Recurrent pregnancy loss | 47 (13.5) | 21 (11.9) | 26 (15.3) | 0.100 |
| Male factor | 87 (25.1) | 53 (29.9) | 34 (20.0) | 0.231 |
| Unexplained | 78 (22.5) | 40 (22.6) | 38 (22.4) | 0.006 |
| Endometriosis | 17 (4.9) | 9 (5.1) | 8 (4.7) | 0.018 |
| Uterine | 11 (3.2) | 8 (4.5) | 3 (1.8) | 0.158 |
| Tubal | 16 (4.6) | 7 (4.0) | 9 (5.3) | 0.064 |
| Single gene disorder | 20 (5.8) | 8 (4.5) | 12 (7.1) | 0.109 |
| Other | 19 (5.5) | 6 (3.4) | 13 (7.6) | 0.187 |
aMeans and standard deviations reported for continuous variables
*Absolute standardized differences calculated between LH/hCG+6 and hCG+7; this represents the difference in means or proportions between the two groups divided by the pooled standard deviation 0.2, 0.5, and 0.8 correspond to small, medium, and large differences respectively. Therefore, smaller standardized differences represent less difference between the two groups
**347 patients who underwent 453 mNC-FET were included in the final analysis. Of these, 149 patients only had LH/hCG+6 cycles, 170 patients only had hCG+7 cycles, and 28 patients underwent cycles with either LH/hCG+6 or hCG+7 transfers depending on the cycle. Therefore, patients who had ever experienced an LH/hCG+6 transfer were grouped together for Table 1 descriptive statistics comparisons