Table 1.

Families with female infertility

Family	Symptom	Gene
1	Empty follicle syndrome	ZP3 mutation
2	Empty follicle syndrome	Unknown
3	Abnormal zona pellucida	Unknown
4	Abnormal zona pellucida	Unknown
5	Thin zona pellucida	Unknown
6	Empty follicle syndrome	Unknown
7	Abnormal zona pellucida	Unknown
8	Abnormal zona pellucida	Unknown
9	Empty follicle syndrome	Unknown
10	Abnormal zona pellucida	Unknown
11	Abnormal zona pellucida	Unknown
12	Abnormal zona pellucida	Unknown
13	Abnormal zona pellucida	Unknown
14	Abnormal zona pellucida	Unknown
15	Abnormal zona pellucida	Unknown
16	Abnormal zona pellucida	ZP3 mutation
17	Abnormal zona pellucida	Unknown

Family 1: ZP3 S173C heterozygous mutation

Family 16: ZP3 mutation, data need to be confirmed