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. 2020 Nov 10;6(1):e10194. doi: 10.1002/btm2.10194

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© 2020 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of American Institute of Chemical Engineers.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Characterization of MC4N and MC12N nanoparticles. (a) Circular dichroism (CD) spectra of the MUC1 aptamer, MC4N‐ and MC12N‐amphiphiles in Milli‐Q water. Schematic representation of the self‐assembled nanoparticles (MUC1 aptamer is shown in blue, C₄ and C₁₂ spacer in gray, and 1,8‐naphthalimide in green) and cryogenic transmission electron microscopy (cryo‐TEM) images (bottom) of (b) spherical micelles formed from MC4N aptamer‐amphiphiles, and (c) cylindrical micelles formed from MC12N aptamer‐amphiphiles