TABLE 1.

Pharmacokinetic parameters in mice after intravenous administration of MUC1 aptamer nanoparticles (mean ± SD, n = 3–4)

Particle	Half‐life of distribution, αt1/2 (min)	Half‐life of elimination, βt1/2 (min)	AUC (nM × min)	Clearance, CL (ml/min/kg)
MC4N‐NO2	0.5 ± 0.5	238.4 ± 94.9	74,138 ± 48,616	39.1 ± 28.3
MC12N‐NO2	1.6 ± 0.5	1085.2 ± 605.4	609,573 ± 292,281	3.9 ± 2.2

Abbreviation: AUC, area under the curve.