TABLE 1.
Overview of all results
| Control (N = 13) | Fibrin (N = 14) | PBMCsec (N = 12) | |
|---|---|---|---|
| Flap necrosis (%) | |||
| Mean | 27.8 | 22.0 | 19.1 |
| SD | 8.6 | 6.2 | 7.2 |
| p‐value | .053 vs. control |
.012 vs. control .293 vs. fibrin |
|
| Seroma (ml) | |||
| Mean | 11.9 | 1.7 | 0.6 |
| SD | 9.7 | 5.3 | 2.0 |
| p‐value | .004 vs. control |
.001 vs. control .523 vs. fibrin |
|
| Flap adherence | |||
| Vital zone | |||
| Mean | 0.46 | 0.71 | 1.00 |
| SD | 0.52 | 0.91 | 1.21 |
| p‐value | .685 vs. control |
.437 vs. control .631 vs. fibrin |
|
| Transition zone | |||
| Mean | 0.54 | 1.29 | 1.58 |
| SD | 0.66 | 0.91 | 0.79 |
| p‐value | .038 vs. control |
.004 vs. control .432 vs. fibrin |
|
| Ischemic zone | |||
| Mean | 0.62 | 2.36 | 2.58 |
| SD | 0.77 | 0.93 | 0.67 |
| p‐value | <.001 vs. control |
<.001 vs. control .631 vs. fibrin |
|
| Tissue edema | |||
| Vital zone | |||
| Mean | 1.38 | 1.21 | 1.17 |
| SD | 0.51 | 0.70 | 0.72 |
| p‐value | .616 vs. control |
.538 vs. control .899 vs. fibrin |
|
| Transition zone | |||
| Mean | 1.38 | 0.86 | 0.67 |
| SD | 0.51 | 0.66 | 0.65 |
| p‐value | .068 vs. control |
.016 vs. control .527 vs. fibrin |
|
| Ischemic zone | |||
| Mean | 2.33 | 2.46 | 2.25 |
| SD | 0.49 | 0.52 | 0.62 |
| p‐value | .611 vs. control |
.843 vs. control .470 vs. fibrin |
|
| Flap perfusion (PU) | |||
| Transition zone | |||
| Preoperative | |||
| Mean | 466.9 | 448.6 | 463.0 |
| SD | 113.6 | 75.5 | 88.1 |
| Postoperative day 3 | |||
| Mean | 525.9 | 564.5 | 612.6 |
| SD | 140.5 | 86.5 | 217.1 |
| p‐value | .292 vs. pre | .001 vs. pre | .026 vs. pre |
| Postoperative day 7 | |||
| Mean | 664.6 | 777.8 | 726.4 |
| SD | 229.6 | 170.6 | 183.7 |
| p‐value |
.032 vs. pre .046 vs. day 3 |
<.001 vs. pre <.001 vs. day 3 |
.003 vs. pre .186 vs. day 3 |
| Ischemic zone | |||
| Preoperative | |||
| Mean | 427.6 | 400.5 | 439.1 |
| SD | 100.8 | 46.0 | 70.0 |
| Postoperative day 3 | |||
| Mean | 135.1 | 123.1 | 138.6 |
| SD | 46.2 | 41.5 | 63.3 |
| p‐value | <.001 vs. pre | <.001 vs. pre | <.001 vs. pre |
| Postoperative day 7 | |||
| Mean | 174.1 | 198.9 | 257.6 |
| SD | 83.4 | 144.0 | 154.7 |
| p‐value |
<.001 vs. pre .038 vs. day 3 |
<.001 vs. pre .057 vs. day 3 |
.007 vs. pre .017 vs. day 3 |
| vWF+ blood vessels/4 fields (N) | |||
| Mean | 70.3 | 67.8 | 85.9 |
| SD | 16.3 | 12.1 | 20.4 |
| p‐value | .651 vs. control |
.045 vs. control .010 vs. fibrin |
|
| Flt‐4+ cells/4 fields (N) | |||
| Mean | 98.2 | 74.5 | 111.0 |
| SD | 53.2 | 46.0 | 66.2 |
| p‐value | .227 vs. control |
.597 vs. control .112 vs. fibrin |