Table 1:

Standard operating procedure for PIPAC anaesthesia.

Location	Operating room with negative pressure/good laminar flow
	Adjacent induction room with capability to have a closed seal from operating room Power points within the room to enable charging of TIVA pumps and equipment Small window to view the patient in the operating theatre and also the monitor to view the vitals of the patient
	Ideally an adjacent room with capability to monitor the patients vitals as shown on the monitor inside in real time
Equipment	Anaesthesia machine with ventilator
	Monitor with vitals monitoring: Electrocardiograph (ECG) monitoring, pulse oximetry, capnography and blood pressure measurement Capability invasive blood pressure monitoring Bispectral index monitoring or entropy
	Monitor should be able to be swivelled towards the window of the adjacent room to enabling viewing
	TIVA pump to run Propofol infusion
	Extension lines for drug infusion
	One way valve tubing or adapter for Propofol infusion (TIVA)
Drugs	Premedication/Antiemetics:
	IV Dexamethasone (4–8 mg)
	IV Ondansetron 8 mg
	Anaesthesia drugs:
	IV Propofol for TIVA infusion
	Opioids: for intubation and intraoperative analgesia Fentanyl (0.5–1 mcg/kg) Morphine (1–2 mg as titrated, 0.1 mg/kg acute postoperative pain control) Remifentanil – is typically not required since PIPAC is not very painful
	Paralytics: IV Atracurium (0.5 mg/kg intubating dose) Suxamethonium (1–1.5 mg/kg for intubation in rapid sequence induction)
	Analgesics: Paracetamol 1 g IV (15 mg/kg dose for patients under 50 kg) NSAIDs (IV Parecoxib 40 mg. For patients <50 kg: 20 mg) Local anaesthetics
	Ropivacaine/Bupivacaine for regional anaesthesia is considered

Drug doses (reference no. [11]).