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. 2021 Jan 23;34(2):355–364. doi: 10.1007/s40620-020-00931-w

Table 3.

Clinical and biological characteristics of the patients at D0 according to tertiles of urinary α1-microglobulin at D0

Tertile 1
< 32 mg/g
(n = 51)
Tertile 2
32–86 mg/g
(n = 50)
Tertile 3
> 86 mg/g
(n = 52)
Kruskal–Wallis test (or exact Chi2 test)
Clinical
Age (years) 66 [57;80]* 65 [58;73]* 77 [70;85] 0.005
Women (%) 49 34 33 ns
Weight (kg) 79 [65;94] 83 [69;93] 75 [68;90] ns
Height (m) 1.68 [1.61;1.79] 1.74 [1.67;1.79] 1.70 [1.65;1.76] ns
Body Mass index (kg/m2) 28 [25;31] 28 [23;30] 27 [23;29] ns
Medical history

Hypertension (%)

Diabetes (%)

Chronic kidney disease (%)

Active cancer (%)

Active smoking(%)

57

29

4*

8

6

62

18

8*

10

2

58

37

38

6

13

ns

ns

< 0.0001

ns

ns

Intensive Care Unit (%) 14 24 27 ns
Severe cases (%) 69* 86 90 0.004
Biological

Creatinine (D0)(mg/dL)

eGFR (mL/min/1.73 m2)

0.87 [0.70;0.99]*

82 [61;95]*

0.91 [0.76;1.06]

82 [61;93]*

1.04 [0.86;1.49]

61 [45;83]

0.007

0.002

C-reactive protein (mg/L) 61 [15;108] 135 [54;216]$ 95 [47;147]$ 0.0001
Leukocyte count (/mm3) 5940 [4260;5940] 6720 [5170;10,100] 6110 [4630;8615] ns
Lymphocyte count (/mm3) 925 [720;1350] 850 [630;1050] 820 [535;1095] ns
Hemoglobin (g/dL) 12.9 [12.0;14.0]* 12.6 [11.6;13.7]* 11.3 [10.5;13.0] 0.0004
Platelets (× 1000/mm3) 248 [179;331]* 247 [189;320]* 180 [140;252] 0.0007
Lactate Dehydrogenase (U/L) 288 [234;382] 372 [274;531]$ 361 [277;446]$ 0.007
D-Dimer (µg/L) 972 [564;1590] 1091 [789;3090] 1050 [776;2208] ns
Albumin (g/L) 37 [33;40] 33 [31;37]$ 33 [29;36]$ 0.0002
Potassium (mmol/L) 4.06 [3.76;4.40] 4.09 [3.91;4.30] 4.14 [3.72;4.48] ns
Sodium (mmol/L) 140 [138;143] 138 [136;140] 140 [137;143] 0.04
Calcium (mmol/L) 2.18 [2.10;2.29] 2.07 [2.00;2.16]$ 2.07 [1.97;2.12]$ 0.000004
Bicarbonate (mmol/L) 25.9 [23.2;27.5] 24.5 [22.5;26.7] 26.1 [23.6;28.9] ns

Ns not significant, eGFR estimated glomerular filtration rate

Dunn’s post hoc test p < 0.05: * proteinuria category stage 3, $ with proteinuria category 1

Chi2 test for categorical variables with Bonferroni correction: * with proteinuria category 3