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. Author manuscript; available in PMC: 2021 Jan 23.
Published in final edited form as: Acta Biomater. 2018 Oct 24;95:165–175. doi: 10.1016/j.actbio.2018.10.028

Fig. 3.

Fig. 3.

Changes in mechanical properties and self-healing of the gallol ECM hydrogels with aging. (A) Frequency sweep (storage (G′) and loss (G″) moduli at 0.5% strain, 37 °C), (B) G′ (1 Hz), and (C) Young’s moduli of gallol (HA-Ga, GEL-Ga) hydrogels at 1:2 mass ratio and 6 wt% initially (Day 0) and 1 day after gelation. (D) Macroscopic self-healing of hydrogels initially (Day 0) and limited self-healing 1 day after gelation. The black arrows indicate the direction of physical forces (F) applied to the hydrogels. Evaluation of disruption and recovery of hydrogels (E) initially (intermittent strains of 0.5 and 1000%) and (F) 1 day after gelation (intermittent strains of 0.5 and 2000%). The black arrow in (E) indicates ~ 80% recovery of G′. The black arrow in (F) indicates a dramatic decrease of G′, corresponding to ~11% of the original value with one round of increased strain. Unpaired t-test, *p < 0.05.