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. 2020 Dec 24;11(1):15. doi: 10.3390/brainsci11010015

Table 1.

Descriptive characteristics and results of the included studies.

Authors/Year Study Design Participants Intervention Comparative Outcomes Variable (Tool)
AbdelGawad et al. (2015) [20] Randomized Controlled Trial Dx: CP
Age (mean ± standard deviation years):
(I) 5.75 ± 0.51
(C) 5.83 ± 0.34
Sex: 60% F, 40% M
Inclusion criteria:
No BTA, MAS 1-2, standing
n = 15
Shock wave therapy and conventional rehabilitation programme
n = 15
conventional rehabilitation programme
Motor impairment (Hmax–Mmax)
Functional independence (gait analysis)
Altindaǧ et al. (2014) [26] Case series Dx: Stroke, CP, SPI
Age (years): 36.6 ± 23.37
Sex: 44% F, 56% M
Inclusion criteria: no BTA, MAS > 2
n = 9
Shock wave therapy and conventional rehabilitation programme
Motor impairment (MAS)
Amelio et al. (2010) [31] Quasi-experimental pre-post Dx: CP
Age (years): 5.83 ± 2.31
Sex: 50% F, 50% M
Inclusion criteria:
no BTA, gait
n = 12
1st session placebo and 2nd session shock wave therapy
Motor Function (PROM)
Motor impairment (MAS)
Functional independence (podobarometry)
Daliri et al. (2015) [18] Quasi-experimental pre-post Dx: Stroke
Age (years): 54.4 ± 9.4
Sex: 20% F, 80% M
Inclusion criteria: no BTA, Stroke > 6 months
n = 15
1st session placebo and 2nd session shock wave therapy
Motor impairment (MAS, BMRS, Hmax-Mmax)
Duan et al. (2016) [30] Randomized Controlled Trial Dx: Stroke
Age (years)
(I) 48.29 ± 12.30
(C) 50.67 ± 14.27
Sex: 48% F, 52% M
Inclusion criteria: no BTA
n = 24
Shock wave therapy and conventional rehabilitation programme
n = 24
conventional rehabilitation programme
Motor impairment (MAS, FMA)
Dymarek et al. (b/2016) [7] Quasi-experimental pre-post Dx: Stroke
Age (years): 63.15 ± 12.60
Sex: 65% F, 35% M
Inclusion criteria: no BTA, MAS > 1+, Stroke > 9 months
n = 20
Shock wave therapy
Motor impairment (MAS)
Electrodiagnostic (EMG, IRT)
Dymarek et al. (a/2016) [6] Randomized Controlled Trial Dx: Stroke
Age (years)
(I) 61.43 ± 12.74
(C) 60.87 ± 9.51
Sex: 43% F, 57% M
Inclusion criteria: no BTA, MAS > 1+,
Stroke > 9 months
n = 30
Shock wave therapy
n = 30
Placebo
Motor impairment (MAS)
Electrodiagnostic (EMG, IRT)
El-Shamy et al. (2014) [22] Randomized Controlled Trial Dx: CP
Age (years)
(I) 6.93 ± 0.8
(C) 6.8 ± 0.77
Sex: 40% F, 60% M
Inclusion criteria:
No BTA, independent gait
n = 15
Shock wave therapy and conventional rehabilitation programme
n = 15
conventional rehabilitation programme
Motor impairment (MAS)
Functional independence (gait analysis)
Gonkova et al. (2013) [8] Quasi-experimental pre-post Dx: CP
Age (years): 4.84 ± 3.11
Sex: 36% F, 64% M
Inclusion criteria:
no BTA
n = 25
1st session placebo and 2nd session radial shock wave therapy
Motor Function (PROM)
Motor impairment (MAS)
Functional independence (podobarometry)
Guo et al. (2019) [1] Randomized Controlled Trial Dx: Stroke
Age (years)
(I–A) 66.79 ± 11.02
(I–B) 67.15 ± 11.23
(I–C) 68.72.0 ± 10.56
(C) 69.72 ± 11.13
Sex: 44% F, 56% M
Inclusion criteria: no BTA, MAS > 1, <4,
Stroke > 6 months
Group A: n = 30
Shock wave therapy and conventional rehabilitation programme
Group B: n = 30
Mirror therapy and conventional rehabilitation programme
Group C: n = 30
Mirror therapy, shock wave and conventional rehabilitation programme
n = 30
conventional rehabilitation programme
Motor impairment (MAS, FMA)
Kim et al. (2013) [28] Quasi-experimental pre-post Dx: stroke
Age (years): 55.4 ± 13.2
Sex: 42% F, 58% M
Inclusion criteria: no BTA, MAS > 1,
Stroke > 9 months
n = 57
Radial shock wave therapy and conventional rehabilitation programme
Motor function (PROM)
Motor impairment (MAS)
Pain (VAS)
Lee et al. (2019) [15] Randomized Controlled Trial Dx: stroke
Age (years):
(I) 50.89 ± 8.81
(C) 44.11 ± 4.07
Sex: 11% F, 89% M
Inclusion criteria:
No BTA
n = 9
Radial shock wave therapy
n = 9
Placebo
Motor function (PROM)
Motor impairment (MAS, FMA)
Electrodiagnostic (echography)
Li et al. (2016) [14] Randomized Controlled Trial Dx: stroke
Age (years):
(I–A) 55.35 ± 3.05
(I–B) 56.80 ± 3.00
(C) 55.95 ± 2.64
Sex: 31% F, 69% M
Inclusion criteria: no BTA, MAS > 1, Stroke > 9 months
Group A: n = 20
3 sessions of radial shock wave therapy
Group B: n = 20
1 session of shock wave therapy
n = 20
Placebo
Motor impairment (MAS, FMA)
Mirea et al. (2014) [16] Quasi-experimental pre-post Dx: CP
Age (months): 99.57 ± 53.74
Sex: 41% F, 59% M
Inclusion criteria: no BTA, MAS 1−3
n = 63
Shock wave therapy
Motor function (GMFM)
Motor impairment (MAS)
Pain (QPS)
Moon et al. (2013) [13] Quasi-experimental pre-post Dx: stroke
Age (years): 52.6 ± 14.9
Sex: 43% F, 57% M
Inclusion criteria: no BTA, MAS > 1+, Stroke > 1 month.
n = 30
1 placebo session and 3 sessions of shock wave therapy
Motor function (PROM)
Motor impairment (MAS, FMA, clonus)
Functional independence (dynamometric isocentric parameters)
Park et al. (2015) [17] Randomized Controlled Trial Dx: CP
Age (years):
(I) 7.0 ± 3.1
(C) 6.8 ± 2.3
Sex: 41% F, 59% M
Inclusion criteria: no BTA, gait
n = 6
3 sessions of shock wave therapy and conventional rehabilitation programme
n = 6
1 shock wave session and 2 placebo sessions and conventional rehabilitation programme
Motor function (PROM)
Motor impairment (MAS)
Radinmehr et al. (2016) [12] Randomized Controlled Trial Dx: stroke
Age (years): 59 ± 13
Sex: 41% F, 59% M
Inclusion criteria: no BTA, independent gait, MAS > 1, Stroke > 1 month
n = 12
Radial shock wave therapy
Motor function (PROM, AROM)
Motor impairment (MAS, PPFT, Hmax–Mmax)
Functional independence (TUG)
Radinmehr et al. (2019) [29] Randomized Controlled Trial Dx: stroke
Age (years):
(I) 56.0 ± 12.3
(C) 56.2 ± 8.4
Sex: 40% F, 60% M
Inclusion criteria: no BTA, gait, MAS > 1, Stroke > 1 month
n = 16
Radial shock wave therapy
n = 16
Ultrasounds
Motor function (PROM, AROM)
Motor impairment (MAS, PPFT, Hmax–Mmax)
Functional independence (TUG)
Santamato et al. (2014) [23] Quasi-experimental pre-post Dx: stroke
Age (years): 57.6 ± 10.8
Sex: 34% F, 66% M
Inclusion criteria: no BTA, MAS > 1 <4
n = 23
Shock wave therapy
Motor impairment (MAS)
Sawan et al. (2017) [25] Quasi experimental Dx: stroke
Age (years):
(I) 50.6 ± 6.7
(C) 84.8 ± 5.9
Inclusion criteria: no BTA, MAS 1−2
n = 20
Shock wave therapy and conventional rehabilitation programme
n = 20
Placebo and conventional rehabilitation programme
Motor function (AROM)
Motor impairment (Hmax–Mmax)
Functional independence (Timed 10 m walk test)
Tirbisch et al. (2015) [40] Randomized Controlled Trial Dx: stroke
Inclusion criteria: no BTA, MAS > 1+
n = 4
Radial shock wave therapy and conventional rehabilitation programme
n = 4
conventional rehabilitation programme
Motor function (PROM)
Motor impairment (MAS, Tardieu Scale)
Vidal et al. (2011) [5] Randomized Controlled Trial Dx: CP
Age (years): 31
Sex: 20% F, 80% M
Inclusion criteria: no BTA
n = 5
Radial shock wave therapy on spastic agonists.
n = 5
Radial shock wave therapy on spastic agonists and antagonists
n = 5
Placebo
Motor function (AROM)
Motor impairment (MAS)
Wang et al. (2016) [24] Case-control Dx: CP
Age (months):
(I) 26.9 ± 13.1
(C) 27.0 ± 14.2
Sex: 33% F, 67% M
Inclusion criteria:
no BTA, MAS 1−4
n = 34
Shock wave therapy and conventional rehabilitation programme
n = 32
Conventional rehabilitation programme
Motor function (PROM, GMFM)
Motor impairment (MAS)
Wu et al. (a/2018) [19] Randomized Controlled Trial Dx: stroke
Age (years):
(I) 59.6 ± 11.3
(C) 60.3 ± 9.9
Sex: 41% F, 59% M
Inclusion criteria: no BTA, gait, MAS 1-4, Stroke > 6 months
n = 16
Radial shock wave therapy
n = 15
Focused shock wave therapy
Motor function (PROM)
Motor impairment (MAS, Tardieu Scale)
Functional independence (Timed 10 m walk test, plantar contact area)
Wu et al. (b/2018) [27] Randomized Controlled Trial Dx: stroke
Age (years):
(I) 60.0 ± 11.1
(C) 62.0 ± 10.2
Sex: 33% F, 67% M
Inclusion criteria: no BTA, Stroke > 6 months
n = 21
Shock wave therapy
n = 21
BTA
Motor function (PROM)
Motor impairment (MAS, FMA)

Dx: diagnosis; CP: Cerebral Palsy; F: Female; M: Male; BTA: Botulinum toxin; MAS: Modified Ashworth Scale, SCI: Spinal Cord Injury; PROM: passive range of movement; BMRS: Brunnstrom stages of motor recovery; FMA: Fugl-Meyer assessment; EMG: electromyography; IRT: thermography; VAS: Visual analogic Scale; GMFM: gross motor function classification system; QPS: questionnaire of pain caused by spasticity; AROM: active range of movement; TUG: Timed up and go test; PPFT: passive plantar flexor torque.