Table 1.
Characteristics (mean, SD) of the entire study population/* the subset of patients with all measurement points and of healthy controls. Group comparisons T0 vs. HC (N = 35, N = 25) were performed with the T-test.
| Parameter (SD) | T0 | T1 | T2 | HC | T0 * | T1 * | T2 * |
|---|---|---|---|---|---|---|---|
| Number of patients/HCs | 35 | 26 | 22 | 25 | 17 | 17 | 17 |
| Duration of illness (months) | 11.47 (8.87) | - | - | - | 8.82 (4.05) | - | - |
| Number of weeks between T0 and T1 | 8.05 (2.82) | 8.65 (2.24) | |||||
| Number of weeks between T1 and T2 (N = 17) | 26.04 (30.58) | 26.04 (30.58) | |||||
| Age (years) a | 15.4 (1.4) | 15.5 (1.5) | 16.0 (1.78) | 16.6 (1.8) | 15.1 (1.4) | 15.3 (1.6) | 15.8 (1.8) |
| Height (cm) b | 163.14 (6.60) | 163.84 (6.95) | 163.85 (6.79) | 166.54 (6.00) | 163.55 (6.96) | 163.64 (7.10) | 163.99 (7.20) |
| Weight (kg) c | 40.68 (5.17) | 46.01 (5.64) | 49.84 (5.83) | 57.46 (6.45) | 41.32(4.77) | 46.19(5.02) | 49.59 (6.22) |
| BMI (kg/m2) d | 15.24 (1.17) | 17.05 (1.15) | 18.51 (1.20) | 20.70 (1.86) | 15.41 (1.03) | 17.16 (1.03) | 18.38 1.28) |
| BMI percentile + | 0.98 (1.59) | 6.86 (6.50) | 16.69 (11.09) | 39.03 (22.10) | 1.30 (1.96) | 7.66 (6.91) | 16.80 (12.31) |
| BMI-SDS +e | −3.04 (1.23) | −1.78 (0.79) | −1.09 (0.53) | −0.32 (0.62) | −2.72 (0.87) | −1.61 (0.52) | −1.11 (0.58) |
+ based on KIGGS survey [41], T0 = admission, T1 = half of target weight, T2 = long term weight gain; close to target weight, HC = healthy controls. a Age T0 vs. HC: T(df = 58) = 3.12, p = 0.0028, b Height T0 vs. HC: T(df = 58) = 2.04, p = 0.046, c Weight T0 vs. HC: T(df = 58) = 11.17, p = 4.41 × 10−16, d BMI T0 vs. HC: T(df = 35.2 adjusted) = 12.95, p = 2.32 × 10−15, e BMI-SDS T0 vs. HC: T(df = 58) = 10.19, p = 1.56 × 10−14.