Table 1.
Comparison of allele frequencies of rs4986790 (D299G) in the toll-like receptor 4 (TLR4) gene between human immunodeficiency virus (HIV)-infected patients in previous studies and matched control populations obtained from the 1000 Genomes Project.
| Population | Country | Year of Publication |
Authors | Cases | Controls | p-Value | Reference | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Allele Frequencies, n (%) | Total, n | Allele Frequencies, n (%) | Total, n | ||||||||
| A | G | A | G | ||||||||
| Caucasian | USA | 2009 | Pine | 374 (93.03) | 28 (6.97) | 201 | 600 (95.85) | 26 (4.15) | 313 | 0.0486 | 1000 Genomes Project, [14] |
| Caucasian | Spain | 2010 | Pulido | 822 (87.82) | 114 (12.18) | 468 | 600 (95.85) | 26 (4.15) | 313 | 5.2687 × 10−8 | 1000 Genomes Project, [15] |
| Caucasian | Greece | 2010 | Papadopoulos | 369 (92.71) | 29 (7.29) | 199 | 600 (95.85) | 26 (4.15) | 313 | 0.0302 | 1000 Genomes Project, [16] |
| Asian | India | 2018 | Vidyant | 277 (86.56) | 43 (13.44) | 160 | 502 (92.96) | 38 (7.04) | 270 | 0.0019 | [13] |