Table 4.
Impairment of Spermatogenesis |
---|
Chemotherapeutic agents |
Calcium channel blockers |
Colchicine |
Sulphasalazine |
Nitrofurantoin |
Corticosteroids |
Opioidsa |
Radioiodine |
Testosterone replacementa |
Androgensa |
Antiandrogenic |
Cimetidine |
Spironolactone |
Flutamide |
Ejaculatory failure |
Alpha blockers |
Serotonin reuptake inhibitors |
a Treatment suppresses spermatogenesis by negative feedback on the hypothalamo–pituitary axis (hypogonadotropic hypogonadism).