Figure 4.

Live EcN decreases severity of EAU if administered at time of disease induction. The EAU severity was analyzed by in vivo fundus biomicroscopy on the 21st and 27th day post-induction (A) and by histological analysis at day 28 post-induction (B) and the differences were quantified by unpaired Mann–Whitney test; * p < 0.05 ** p < 0.01; n = 8 (placebo prevention), 13 (EcN prevention), 19 (placebo early + late treatment), 22 (EcN early + late treatment), 10 (placebo late treatment) and 20 (EcN late treatment) in total, graphs show individual values and red lines represent mean. Black squares represent individual inflammation severity scores from the placebo group and open circles from the EcN group.