Figure 3.

Representative kinematic profiles of the shoulder (top) and hand (bottom) of a 65-year-old patient with FXTAS (dashed orange line) and an age-matched healthy control (solid blue line) when they walked to reach and lift the small box. The FXTAS patient showed a prolonged reaching duration (left), decreased maximum reaching velocity of the shoulder and hand (middle, highlighted in a cyan box), and more oscillatory and jerkier joint movement (right) relative to the control participant. Time series were graphed from the reaching onset to offset. Jerk trajectories are shown in absolute values (cm/s³).