Table 2.
Demographic characteristics and aortic root diameter measurements in patients with the mild form and severe form of MPS II (n = 49).
| Covariate | MPS II (Mild) | MPS II (Severe) |
|---|---|---|
| n | 22 | 27 |
| Gender (M/F) | 22/0 | 27/0 |
| Age (years) | 7.7 (5.9) | 6.7 (4.2) |
| Age range (years) | 0.1–19.1 | 0.1–13.2 |
| Height z score | −2.03 (3.23) | −1.63 (2.38) |
| Weight z score | 0.06 (1.62) | 0.03 (2.19) |
| BSA (m2) | 0.82 (0.29) | 0.75 (0.21) |
| AoD (cm) | 2.10 (0.54) | 2.10 (0.42) |
| AoD z score | 1.88 (1.43) | 2.32 (1.44) |
| AoD z score > 2, n (%) | 10 (45%) | 15 (56%) |
| r value (AoD z score versus age) | 0.642 | 0.180 |
| p-value | p < 0.01 | p > 0.05 |
Data are mean (standard deviation). MPS, mucopolysaccharidosis; M/F: male/female; BSA: body surface area; AoD, aortic root diameter.