Table 1.
Cross-validation results and detection thresholds for biosynthetic domains used in the pipeline. The detection thresholds are referred to as domT by the HMMER manual [15].
| Abbreviation | Name | F1 | Precision | Recall | Support | Threshold |
|---|---|---|---|---|---|---|
| ACP | Acyl carrier protein | 0.96 | 1.00 | 0.91 | 4315 | 13.9 |
| AT | Acyltransferase | 1.00 | 1.00 | 1.00 | 2893 | 47.4 |
| A | Adenylation domain | 1.00 | 1.00 | 0.99 | 3092 | 19.6 |
| CAL | Coenzyme A ligase | 0.94 | 0.89 | 1.00 | 180 | 221.8 |
| C | Condensation domain | 1.00 | 1.00 | 1.00 | 2734 | 25.9 |
| DH2 1 | Dehydratase | 0.98 | 0.95 | 1.00 | 414 | 33.2 |
| DH | Dehydratase | 0.99 | 1.00 | 0.99 | 1469 | 31.1 |
| DHt 2 | Dehydratase | 0.88 | 0.98 | 0.81 | 113 | 44.3 |
| ER | Enoylreductase | 1.00 | 1.00 | 1.00 | 646 | 68.8 |
| E | Epimerization domain | 1.00 | 0.99 | 1.00 | 424 | 60.4 |
| KR | Ketoreductase | 1.00 | 1.00 | 1.00 | 3374 | 20 |
| KS | Keto-synthase | 1.00 | 1.00 | 1.00 | 3970 | 72 |
| PCP | Peptide carrier protein | 0.97 | 0.95 | 1.00 | 2785 | 21.9 |
| TD | Reductive Thioesterase | 1.00 | 1.00 | 1.00 | 118 | 42.1 |
| TE | Thioesterase | 1.00 | 1.00 | 1.00 | 824 | 36.5 |
| bACP | β-branching acyl carrier protein | 0.59 | 0.42 | 1.00 | 155 | 28.9 |
| cMT | C-Methyltransferase | 1.00 | 0.99 | 1.00 | 326 | 104.7 |
| nMT | N-Methyltransferase | 0.99 | 1.00 | 0.99 | 173 | 42.7 |
| oMT | O-Methyltransferase | 0.99 | 0.99 | 0.99 | 184 | 70.6 |
| tAT_d | Trans-acyltransferase docking domain | 0.98 | 0.97 | 1.00 | 665 | 50 |
| Macro avg. | 0.97 | 0.96 | 0.99 | 30,144 | ||
| Micro avg. | 0.99 | 0.99 | 0.99 | 30,144 | ||
| Weighted avg. | 0.99 | 0.99 | 0.99 | 30,144 |